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Singapore Clinical Trial: A Phase 3, Randomized, Double-blind, Placebo-controlled Study of Investigator Choice of Chemotherapy (modified FOLFIRINOX or Gemcitabine plus Nab-paclitaxel) with or without Zoldonrasib (RMC 9805) as First-line Treatment in Patients with Metastatic KRAS G12D-mutated Pancreatic Adenocarcinoma (RASolute 305)

Singapore, Aug. 20 -- The Health Sciences Authority received information related to the study titled 'A Phase 3, Randomized, Double-blind, Placebo-controlled Study of Investigator Choice of Chemothera... Read More


Clinical Trial: Preoperative Anxiety in Patients Undergoing RIRS and PCNL

U.S., Aug. 20 -- ClinicalTrials.gov registry received information related to the study (NCT07772830) titled 'Preoperative Anxiety in Patients Undergoing RIRS and PCNL' on Aug. 14. Brief Summary: This... Read More


Clinical Trial: Platform for End-of-life Awareness, Conversations, and Education (PEACE) Among Registered Nurses

U.S., Aug. 20 -- ClinicalTrials.gov registry received information related to the study (NCT07774468) titled 'Platform for End-of-life Awareness, Conversations, and Education (PEACE) Among Registered N... Read More


Singapore Clinical Trial: A Phase 1, Investigator- and Participant-Blinded, Placebo-Controlled, Randomized, Multiple-Dose Study to Evaluate the Gastric Emptying Delay, Pharmacokinetics, Safety, and Tolerability of Eloralintide in Participants with Obesity or Overweight

Singapore, Aug. 20 -- The Health Sciences Authority received information related to the study titled 'A Phase 1, Investigator- and Participant-Blinded, Placebo-Controlled, Randomized, Multiple-Dose St... Read More


Clinical Trial: Effect of AI-Assisted Discharge Education on Parents of Children With Bronchitis/Bronchiolitis

U.S., Aug. 20 -- ClinicalTrials.gov registry received information related to the study (NCT07774494) titled 'Effect of AI-Assisted Discharge Education on Parents of Children With Bronchitis/Bronchioli... Read More


Clinical Trial: GPX4 Expression After Kono-S vs Conventional Anastomosis

U.S., Aug. 20 -- ClinicalTrials.gov registry received information related to the study (NCT07772037) titled 'GPX4 Expression After Kono-S vs Conventional Anastomosis' on July 09. Brief Summary: Crohn... Read More


Singapore Clinical Trial: A Phase 1 randomized, double-blind, placebo-controlled, single-ascending-dose study investigating the safety and tolerability of ARD001 in healthy adult subjects and a Phase 2 open-label, multiple-dose study in adult subjects with hemophilia A

Singapore, Aug. 20 -- The Health Sciences Authority received information related to the study titled 'A Phase 1 randomized, double-blind, placebo-controlled, single-ascending-dose study investigating ... Read More


Singapore Clinical Trial: A Multinational, Multicenter Study With an Open-Label Phase 1b and a Randomized, Double-Blind, Placebo-Controlled Phase 3 Followed by an Open-Label Extension to Assess the Efficacy, Safety, Tolerability, and Pharmacokinetics of Radiprodil in Participants With GRIN-Related Neurodevelopmental Disorder

Singapore, Aug. 20 -- The Health Sciences Authority received information related to the study titled 'A Multinational, Multicenter Study With an Open-Label Phase 1b and a Randomized, Double-Blind, Pla... Read More


Clinical Trial: Oral Galactose as a Substrate for Post-Exercise Skeletal Muscle Glycogen Repletion in Individuals With Type 1 Diabetes

U.S., Aug. 20 -- ClinicalTrials.gov registry received information related to the study (NCT07774780) titled 'Oral Galactose as a Substrate for Post-Exercise Skeletal Muscle Glycogen Repletion in Indiv... Read More


Singapore Clinical Trial: A Global, Multicenter, Prospective, Controlled, Open-Label Pivotal Study of Iodofalan (131I) Solution for Injection (TLX101-Tx) Plus Lomustine Versus Lomustine Alone in Patients with Radiographically Confirmed Recurrent Glioblastoma at First Recurrence (IPAX-3)

Singapore, Aug. 20 -- The Health Sciences Authority received information related to the study titled 'A Global, Multicenter, Prospective, Controlled, Open-Label Pivotal Study of Iodofalan (131I) Solut... Read More